La dieta alta en grasas no solo no promueve la formación de las placas de ateroma (esos acúmulos mal achacados al colesterol, que obstruyen el flujo sanguíneo provocando trombos, embolias y ataques al corazón), sino que las atenúa.
En este “ketómetro” de trayectoria sinuosa conoceremos algunos marcadores que se utilizan para evaluar tu riesgo cardiovascular. Y les cederemos la palabra…
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Referencias de este “ketómetro”
(por orden de aparición)
Diamond, D. M., O’Neill, B. J., & Volek, J. S. (2020). Low carbohydrate diet: Are concerns with saturated fat, lipids, and cardiovascular disease risk justified? Current Opinion in Endocrinology, Diabetes, and Obesity, 27(5), 291-300. https://doi.org/10.1097/MED.0000000000000568
Rosch, P., Kendrick, M., Harcombe, Z., Ravnskov, U., Alabdulgader, A., McCully, K., Hamazaki, T., Okuyama, H., Diamond, D., & Monteiro, C. (2020). Lipid Lunacy: Diet delusions and what really causes heart disease.
Aronson, D., & Rayfield, E. J. (2002). How hyperglycemia promotes atherosclerosis: Molecular mechanisms. Cardiovascular Diabetology, 1(1), 1. https://doi.org/10.1186/1475-2840-1-1
Hoogeveen, R. C., Gaubatz, J. W., Sun, W., Dodge, R. C., Crosby, J. R., … & Ballantyne, C. M. (2014). Small Dense Low-Density Lipoprotein-Cholesterol Concentrations Predict Risk for Coronary Heart Disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 34(5), 1069-1077. https://doi.org/10.1161/ATVBAHA.114.303284
Kendrick, M. (2021). The Clot Thickens: The enduring mystery of heart disease.
Itabe, H., Obama, T., & Kato, R. (2011). The Dynamics of Oxidized LDL during Atherogenesis. Journal of Lipids, 2011, 418313. https://doi.org/10.1155/2011/418313
Armando, I., Villar, V. A. M., & Jose, P. A. (2015). Genomics and pharmacogenomics of salt-sensitive hypertension Minireview. Current hypertension reviews, 11(1), 49-56.
Doukky, R., Avery, E., Mangla, A., Collado, F. M., Ibrahim, Z., …, & Powell, L. H. (2016). Impact of Dietary Sodium Restriction on Heart Failure Outcomes. JACC. Heart Failure, 4(1), 24-35. https://doi.org/10.1016/j.jchf.2015.08.007
Takaya, J., Higashino, H., & Kobayashi, Y. (2004). Intracellular magnesium and insulin resistance. Magnesium Research, 17(2), 126-136.
Furman, D., Campisi, J., Verdin, E., Carrera-Bastos, P., Targ, S., … & Slavich, G. M. (2019). Chronic inflammation in the etiology of disease across the life span. Nature Medicine, 25(12), 1822-1832. https://doi.org/10.1038/s41591-019-0675-0
Youm, Y.-H., Nguyen, K. Y., Grant, R. W., Goldberg, E. L., D’Agostino, D., … & Dixit, V. D. (2015). The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease. Nature Medicine, 21(3), 263-269. https://doi.org/10.1038/nm.3804
Newman, J. C., & Verdin, E. (2014). β-hydroxybutyrate: Much more than a metabolite. Diabetes Research and Clinical Practice, 106(2), 173-181. https://doi.org/10.1016/j.diabres.2014.08.009
DiNicolantonio, J. J., Lucan, S. C., & O’Keefe, J. H. (2016). The Evidence for Saturated Fat and for Sugar Related to Coronary Heart Disease. Progress in Cardiovascular Diseases, 58(5), 464-472. https://doi.org/10.1016/j.pcad.2015.11.006