Km 10.- El keto y la salud cardiovascular

La dieta alta en grasas no solo no promueve la formación de las placas de ateroma (esos acúmulos mal achacados al colesterol, que obstruyen el flujo sanguíneo provocando trombos, embolias y ataques al corazón), sino que las atenúa.

En este “ketómetro” de trayectoria sinuosa conoceremos algunos marcadores que se utilizan para evaluar tu riesgo cardiovascular. Y les cederemos la palabra…

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Referencias de este “ketómetro”

(por orden de aparición)

Diamond, D. M., O’Neill, B. J., & Volek, J. S. (2020). Low carbohydrate diet: Are concerns with saturated fat, lipids, and cardiovascular disease risk justified? Current Opinion in Endocrinology, Diabetes, and Obesity, 27(5), 291-300. https://doi.org/10.1097/MED.0000000000000568

Rosch, P., Kendrick, M., Harcombe, Z., Ravnskov, U., Alabdulgader, A., McCully, K., Hamazaki, T., Okuyama, H., Diamond, D., & Monteiro, C. (2020). Lipid Lunacy: Diet delusions and what really causes heart disease.

Aronson, D., & Rayfield, E. J. (2002). How hyperglycemia promotes atherosclerosis: Molecular mechanisms. Cardiovascular Diabetology, 1(1), 1. https://doi.org/10.1186/1475-2840-1-1

Hoogeveen, R. C., Gaubatz, J. W., Sun, W., Dodge, R. C., Crosby, J. R., … & Ballantyne, C. M. (2014). Small Dense Low-Density Lipoprotein-Cholesterol Concentrations Predict Risk for Coronary Heart Disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 34(5), 1069-1077. https://doi.org/10.1161/ATVBAHA.114.303284

Kendrick, M. (2021). The Clot Thickens: The enduring mystery of heart disease.

Itabe, H., Obama, T., & Kato, R. (2011). The Dynamics of Oxidized LDL during Atherogenesis. Journal of Lipids, 2011, 418313. https://doi.org/10.1155/2011/418313

Armando, I., Villar, V. A. M., & Jose, P. A. (2015). Genomics and pharmacogenomics of salt-sensitive hypertension Minireview. Current hypertension reviews, 11(1), 49-56.

Doukky, R., Avery, E., Mangla, A., Collado, F. M., Ibrahim, Z., …, & Powell, L. H. (2016). Impact of Dietary Sodium Restriction on Heart Failure Outcomes. JACC. Heart Failure, 4(1), 24-35. https://doi.org/10.1016/j.jchf.2015.08.007

Takaya, J., Higashino, H., & Kobayashi, Y. (2004). Intracellular magnesium and insulin resistance. Magnesium Research, 17(2), 126-136.

Furman, D., Campisi, J., Verdin, E., Carrera-Bastos, P., Targ, S., … & Slavich, G. M. (2019). Chronic inflammation in the etiology of disease across the life span. Nature Medicine, 25(12), 1822-1832. https://doi.org/10.1038/s41591-019-0675-0

Youm, Y.-H., Nguyen, K. Y., Grant, R. W., Goldberg, E. L., D’Agostino, D., … & Dixit, V. D. (2015). The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease. Nature Medicine, 21(3), 263-269. https://doi.org/10.1038/nm.3804

Newman, J. C., & Verdin, E. (2014). β-hydroxybutyrate: Much more than a metabolite. Diabetes Research and Clinical Practice, 106(2), 173-181. https://doi.org/10.1016/j.diabres.2014.08.009

DiNicolantonio, J. J., Lucan, S. C., & O’Keefe, J. H. (2016). The Evidence for Saturated Fat and for Sugar Related to Coronary Heart Disease. Progress in Cardiovascular Diseases, 58(5), 464-472. https://doi.org/10.1016/j.pcad.2015.11.006